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Ombrabulin hydrochloride

CAS No. 253426-24-3

Ombrabulin hydrochloride ( AVE-8062;AVE-8062A;AC-7700 )

Catalog No. M13754 CAS No. 253426-24-3

A novel combretastatin A-4 derivative that strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organ.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ombrabulin hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel combretastatin A-4 derivative that strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organ.
  • Description
    A novel combretastatin A-4 derivative that strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organ; a vascular-disrupting agent.Ovarian Cancer Phase 2 Clinical
  • Synonyms
    AVE-8062;AVE-8062A;AC-7700
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Cancer
  • Indication
    Ovarian Cancer

Chemical Information

  • CAS Number
    253426-24-3
  • Formula Weight
    438.90
  • Molecular Formula
    C21H27ClN2O6
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO; Methanol: ≥ 30 mg/mL
  • SMILES
    O=C(NC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC)[C@@H](N)CO.[H]Cl
  • Chemical Name
    Propanamide, 2-amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]-, hydrochloride (1:1), (2S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hori K, et al. Br J Cancer. 2002 May 20;86(10):1604-14.
2. Kim TJ, et al. Cancer Res. 2007 Oct 1;67(19):9337-45.
3. Sessa C, et al. Clin Cancer Res. 2013 Sep 1;19(17):4832-42.
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